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Stock-Based Compensation - Summary of Stock Options Activity under Plans (Details)
$ / shares in Units, $ in Thousands
12 Months Ended
Dec. 31, 2022
USD ($)
$ / shares
shares
Share-Based Payment Arrangement [Abstract]  
Stock Options Outstanding Balance at December 31, 2021 | shares 344,713
Stock Options Outstanding Options granted | shares 357,798
Stock Options Outstanding Options exercised | shares 0
Stock Options Outstanding Options forfeited/cancelled | shares (119,954)
Stock Options Outstanding Balance at December 31, 2022 | shares 582,557
Stock Options Outstanding Vested and expected to vest at December 31, 2022 | shares 582,557
Stock Options Outstanding Vested and exercisable at December 31, 2021 | shares 164,576
Weighted-Average Exercise Price Balance at December 31, 2021 | $ / shares $ 118.03
Weighted-Average Exercise Price Options granted | $ / shares 20.90
Weighted-Average Exercise Price Options exercised | $ / shares 0
Weighted-Average Exercise Price Options forfeited/cancelled | $ / shares 110.67
Weighted-Average Exercise Price Balance at December 31, 2022 | $ / shares 59.89
Weighted-Average Exercise Price Vested and expected to vest at December 30, 2021 | $ / shares 59.89
Weighted-Average Exercise Price Vested and exercisable at December 30, 2021 | $ / shares $ 113.99
Weighted-Average Remaining Contractual Term (in years) Balance at December 31, 2022 8 years 3 months
Weighted-Average Remaining Contractual Term (in years) Vested and expected to vest at December 31, 2022 8 years 3 months
Weighted-Average Remaining Contractual Term (in years) Vested and exercisable at December 31, 2022 6 years 2 months 1 day
Aggregate Intrinsic Value Balance at December 31, 2022 | $ $ 0
Aggregate Intrinsic Value Vested and expected to vest at December 31, 2022 | $ 0
Aggregate Intrinsic Value Vested and exercisable at December 31, 2022 | $ $ 0