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License Agreements - Additional Information (Details)
1 Months Ended 3 Months Ended 12 Months Ended
Jan. 31, 2020
USD ($)
$ / shares
shares
Dec. 31, 2022
USD ($)
shares
Dec. 31, 2022
USD ($)
Item
shares
Dec. 31, 2021
USD ($)
shares
Dec. 31, 2020
USD ($)
Dec. 31, 2012
Item
Jan. 09, 2020
USD ($)
$ / shares
Research And Development Arrangement Contract To Perform For Others [Line Items]              
Number of common shares | shares   43,498,617 43,498,617 37,816,794      
Value of common stock   $ 4,350 $ 4,350 $ 3,782      
Research and development expense recognized     $ 57,947,447 $ 58,060,725 $ 70,244,579    
License Agreement | Antecip              
Research And Development Arrangement Contract To Perform For Others [Line Items]              
Number of exclusive license agreements | Item     3     3  
License agreement royalty as a percent of net sales   3.00%          
License agreement royalty, maximum reduction percent as a result of required third party payments           50.00%  
License agreement term, from first commercial sale           10 years  
License Agreement | Antecip | AXS-05              
Research And Development Arrangement Contract To Perform For Others [Line Items]              
License agreement royalty as a percent of net sales     3.00%     3.00%  
Pfizer Inc | License Agreement              
Research And Development Arrangement Contract To Perform For Others [Line Items]              
Number of common shares | shares 82,019            
Value of common stock $ 8,000,000.0            
Prior trading days 10 days            
Share price | $ / shares $ 97.538            
Upfront cash payment $ 3,000,000.0            
Fair value share price | $ / shares             $ 87.24
Fair value of common stock             $ 7,200,000
Research and development expense recognized         $ 10,200,000    
Future milestone payments   $ 323,000,000 $ 323,000,000        
Milestone payments or royalties     $ 0