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Loan and Security Agreement - Additional Information (Details) - USD ($)
12 Months Ended
Jan. 31, 2023
Oct. 14, 2021
Dec. 31, 2022
Dec. 31, 2021
Dec. 31, 2020
Jan. 09, 2023
Mar. 27, 2022
Mar. 31, 2019
Line Of Credit Facility [Line Items]                
Loss on extinguishment of debt         $ 1,247,012      
Interest expense     $ 8,176,264 $ 4,616,597 2,362,083      
Amortization of debt issuance costs     668,051 554,493 469,676      
Amortization of debt discount     1,482,678 1,077,015 786,750      
Third Amendment To Loan and Security Agreement | Subsequent Event                
Line Of Credit Facility [Line Items]                
Maximum loan amount $ 350,000,000              
Warrants                
Line Of Credit Facility [Line Items]                
Amortization of debt discount     814,627 $ 522,522 $ 317,074      
Hercules Capital Inc | Term Loan | Subsequent Event                
Line Of Credit Facility [Line Items]                
Maximum loan amount 350,000,000         $ 350,000,000    
Hercules Capital Inc | Third Amendment To Loan and Security Agreement | Term Loan | Subsequent Event                
Line Of Credit Facility [Line Items]                
Maximum loan amount 55,000,000.0         $ 55,000,000.0    
Prepayment Occurs Prior to First Anniversary of Closing Date | Third Amendment To Loan and Security Agreement | Subsequent Event                
Line Of Credit Facility [Line Items]                
Maximum loan amount $ 300,000,000              
Term Loan 2020                
Line Of Credit Facility [Line Items]                
Debt instrument maturity, month and year   2026-10            
Base interest rate   8.95%            
Final payment fee     $ 2,910,000          
Percentage of final payment fee     4.50%          
Minimum different from remaining percentage of cash flow   10.00%            
Term Loan 2020 | Subsequent Event                
Line Of Credit Facility [Line Items]                
Base interest rate 9.95%              
Increase in minimum cash requirement amount $ 30,000,000              
Percentage of facility fee to be paid 0.75%              
Term Loan 2020 | Prime Rate                
Line Of Credit Facility [Line Items]                
Interest rate basis   5.70%            
Term Loan 2020 | Prime Rate | Subsequent Event                
Line Of Credit Facility [Line Items]                
Interest rate basis 2.20%              
Term Loan 2020 | Prime Rate | Maximum                
Line Of Credit Facility [Line Items]                
Interest rate basis   10.70%            
Term Loan 2020 | Prime Rate | Maximum | Subsequent Event                
Line Of Credit Facility [Line Items]                
Interest rate basis 10.70%              
Term Loan 2020 | Hercules Capital Inc                
Line Of Credit Facility [Line Items]                
Maximum loan amount   $ 300,000,000            
Term Loan 2020 | Prepayment Occurs Prior to First Anniversary of Closing Date                
Line Of Credit Facility [Line Items]                
Percentage of prepayment penalty     2.00%          
Term Loan 2020 | Outstanding principle and advances under the loans agreement exceeds 55 million                
Line Of Credit Facility [Line Items]                
Minimum cash to be maintain as a first priority security interest     $ 40,000,000.0          
Period of unpaid invoices amount maintain as security     180 days          
Long term debt upon milestone achievement amount     $ 25,000,000.0          
Long term debt increase decrease threshold amount     40,000,000.0          
Term Loan 2020 | Outstanding principle and advances under the loans agreement exceeds 65 million                
Line Of Credit Facility [Line Items]                
Minimum amount of market capital to be maintained     $ 1,000,000,000.0          
Minimum percentage of cash to be maintained as a security following market capitalization condition     50.00%          
Minimum percentage of cash to be maintained as a security     85.00%          
Term Loan 2020 | Outstanding principle and advances under the loans agreement exceeds 65 million | AXS-05 and AXS-07                
Line Of Credit Facility [Line Items]                
Minimum product revenue percent     60.00%          
Term Loan 2020 | Prepayment Occurs on or After First Anniversary and Prior to Second Anniversary of the Closing Date                
Line Of Credit Facility [Line Items]                
Percentage of prepayment penalty     1.50%          
Term Loan 2020 | Prepayment Occurs on or After Second Anniversary and Prior to Third Anniversary of Closing Date                
Line Of Credit Facility [Line Items]                
Percentage of prepayment penalty     1.00%          
Tranche One | Subsequent Event                
Line Of Credit Facility [Line Items]                
Maximum loan amount $ 95,000,000              
2020 Warrants                
Line Of Credit Facility [Line Items]                
Maximum loan amount   60,000,000.0            
Remaining credit facility to be drawn             $ 95,000,000.0  
2020 Warrants | Second Amendment To Loan and Security Agreement                
Line Of Credit Facility [Line Items]                
Maximum loan amount             45,000,000.0  
Term loan 2020 tranche two                
Line Of Credit Facility [Line Items]                
Maximum loan amount   100,000,000.0            
Term loan 2020 tranche three                
Line Of Credit Facility [Line Items]                
Maximum loan amount   20,000,000.0            
Term loan 2020 tranche four                
Line Of Credit Facility [Line Items]                
Maximum loan amount   55,000,000.0         50,000,000.0  
Term loan 2020 tranche five                
Line Of Credit Facility [Line Items]                
Maximum loan amount             35,000,000.0  
Remaining credit facility to be drawn   $ 75,000,000.0            
2019 Term Loan                
Line Of Credit Facility [Line Items]                
Maximum loan amount               $ 24,000,000.0
Tranche One Sub-Tranche One | Subsequent Event                
Line Of Credit Facility [Line Items]                
Maximum loan amount 95,000,000              
Tranche One Sub Tranche Two | Subsequent Event                
Line Of Credit Facility [Line Items]                
Maximum loan amount 55,000,000              
Tranche One Sub Tranche Three | Subsequent Event                
Line Of Credit Facility [Line Items]                
Maximum loan amount 30,000,000              
Tranche One Sub Tranche Four | Subsequent Event                
Line Of Credit Facility [Line Items]                
Maximum loan amount 35,000,000              
Tranche One Sub Tranche Five | Subsequent Event                
Line Of Credit Facility [Line Items]                
Maximum loan amount 35,000,000              
Tranche Two Sub Tranche One                
Line Of Credit Facility [Line Items]                
Maximum loan amount             35,000,000.0  
Tranche Two Sub Tranche One | Subsequent Event                
Line Of Credit Facility [Line Items]                
Maximum loan amount 35,000,000              
Tranche Two Sub-Tranche Two                
Line Of Credit Facility [Line Items]                
Maximum loan amount             35,000,000.0  
Tranche Two Sub-Tranche Two | Subsequent Event                
Line Of Credit Facility [Line Items]                
Maximum loan amount 35,000,000              
Tranche Two Sub-Tranche Three                
Line Of Credit Facility [Line Items]                
Maximum loan amount             30,000,000.0  
Tranche Two Sub-Tranche Three | Subsequent Event                
Line Of Credit Facility [Line Items]                
Maximum loan amount 30,000,000              
Tranche Three Sub Tranche One                
Line Of Credit Facility [Line Items]                
Maximum loan amount             15,000,000.0  
Tranche Three Sub Tranche One | Subsequent Event                
Line Of Credit Facility [Line Items]                
Maximum loan amount 15,000,000              
Tranche Three Sub Tranche Two                
Line Of Credit Facility [Line Items]                
Maximum loan amount             $ 5,000,000.0  
Tranche Three Sub Tranche Two | Subsequent Event                
Line Of Credit Facility [Line Items]                
Maximum loan amount 5,000,000              
Tranche Two Sub Tranches To One Tranche | Subsequent Event                
Line Of Credit Facility [Line Items]                
Maximum loan amount 25,000,000              
Tranche Three Sub Tranches to One Tranche | Subsequent Event                
Line Of Credit Facility [Line Items]                
Maximum loan amount $ 75,000,000