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The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE

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COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ELEVEN BIOTHERAPEUTICS, INC. COM 286221106 5,084 4,841,591 SH   DFND 1,2,3 4,841,591 0 0
ZAFGEN, INC. COM 98885E103 1,567 210,371 SH   DFND 1,2,3 210,371 0 0
CYTOMX THERAPEUTICS, INC. COM 23284F105 29,029 1,020,348 SH   DFND 1,2,3 1,020,348 0 0
KALA PHARMACEUTICALS INC. COM 483119103 26,190 1,654,425 SH   DFND 1,2,3 1,654,425 0 0
RHYTHM PHARMACEUTICALS, INC. COM 76243J105 79,231 3,981,437 SH   DFND 1,2,3 3,981,437 0 0