<SEC-DOCUMENT>0001576280-25-000004.txt : 20250103 <SEC-HEADER>0001576280-25-000004.hdr.sgml : 20250103 <ACCEPTANCE-DATETIME>20250103175244 ACCESSION NUMBER: 0001576280-25-000004 CONFORMED SUBMISSION TYPE: 4 PUBLIC DOCUMENT COUNT: 1 CONFORMED PERIOD OF REPORT: 20241231 FILED AS OF DATE: 20250103 DATE AS OF CHANGE: 20250103 REPORTING-OWNER: OWNER DATA: COMPANY CONFORMED NAME: Eltoukhy Helmy CENTRAL INDEX KEY: 0001752968 ORGANIZATION NAME: FILING VALUES: FORM TYPE: 4 SEC ACT: 1934 Act SEC FILE NUMBER: 001-38683 FILM NUMBER: 25508227 MAIL ADDRESS: STREET 1: 3100 HANOVER STREET CITY: PALO ALTO STATE: CA ZIP: 94304 ISSUER: COMPANY DATA: COMPANY CONFORMED NAME: Guardant Health, Inc. CENTRAL INDEX KEY: 0001576280 STANDARD INDUSTRIAL CLASSIFICATION: SERVICES-MEDICAL LABORATORIES [8071] ORGANIZATION NAME: 08 Industrial Applications and Services IRS NUMBER: 454139254 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 BUSINESS ADDRESS: STREET 1: 3100 HANOVER STREET CITY: PALO ALTO STATE: CA ZIP: 94304 BUSINESS PHONE: 855-698-8887 MAIL ADDRESS: STREET 1: 3100 HANOVER STREET CITY: PALO ALTO STATE: CA ZIP: 94304 </SEC-HEADER> <DOCUMENT> <TYPE>4 <SEQUENCE>1 <FILENAME>wk-form4_1735944758.xml <DESCRIPTION>FORM 4 <TEXT> <XML> <?xml version="1.0"?> <ownershipDocument> <schemaVersion>X0508</schemaVersion> <documentType>4</documentType> <periodOfReport>2024-12-31</periodOfReport> <notSubjectToSection16>0</notSubjectToSection16> <issuer> <issuerCik>0001576280</issuerCik> <issuerName>Guardant Health, Inc.</issuerName> <issuerTradingSymbol>GH</issuerTradingSymbol> </issuer> <reportingOwner> <reportingOwnerId> <rptOwnerCik>0001752968</rptOwnerCik> <rptOwnerName>Eltoukhy Helmy</rptOwnerName> </reportingOwnerId> <reportingOwnerAddress> <rptOwnerStreet1>3100 HANOVER STREET</rptOwnerStreet1> <rptOwnerStreet2></rptOwnerStreet2> <rptOwnerCity>PALO ALTO</rptOwnerCity> <rptOwnerState>CA</rptOwnerState> <rptOwnerZipCode>94304</rptOwnerZipCode> <rptOwnerStateDescription></rptOwnerStateDescription> </reportingOwnerAddress> <reportingOwnerRelationship> <isDirector>1</isDirector> <isOfficer>1</isOfficer> <isTenPercentOwner>0</isTenPercentOwner> <isOther>0</isOther> <officerTitle>Co-Chief Executive Officer</officerTitle> </reportingOwnerRelationship> </reportingOwner> <aff10b5One>0</aff10b5One> <nonDerivativeTable> <nonDerivativeTransaction> <securityTitle> <value>Common Stock</value> </securityTitle> <transactionDate> <value>2024-12-31</value> </transactionDate> <transactionCoding> <transactionFormType>4</transactionFormType> <transactionCode>M</transactionCode> <equitySwapInvolved>0</equitySwapInvolved> </transactionCoding> <transactionAmounts> 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The amount retained by the Company was not in excess of the amount of the tax liability.</footnote> <footnote id="F2">This restricted stock unit award was granted on March 18, 2024 and vests in four equal installments on the last day of each calendar quarter, March 31st, June 30th, September 30th, and December 31st, 2024.</footnote> <footnote id="F3">Not applicable for Restricted Stock Units.</footnote> <footnote id="F4">This restricted stock unit award was granted on March 18, 2024 and vests with respect to 1/3 of the shares on January 1, 2025, and then quarterly for the remaining twenty-four months.</footnote> </footnotes> <remarks></remarks> <ownerSignature> <signatureName>/s/ John G. Saia, as attorney-in-fact for Helmy Eltoukhy</signatureName> <signatureDate>2025-01-03</signatureDate> </ownerSignature> </ownershipDocument> </XML> </TEXT> </DOCUMENT> </SEC-DOCUMENT>