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Fair Value Measurements, Cash Equivalents and Marketable Securities - Narrative (Details) - USD ($)
1 Months Ended 3 Months Ended 9 Months Ended
Jul. 31, 2022
May 31, 2018
Sep. 30, 2023
Sep. 30, 2022
Sep. 30, 2023
Sep. 30, 2022
Dec. 31, 2022
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]              
Realized gain (loss) on marketable debt securities     $ 0 $ 0 $ 0 $ 0  
Recognition of credit losses     0 0 0 0  
SoftBank              
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]              
Threshold percentage of fair value that is no less than internal rate of return   20.00%          
Lunit Inc.              
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]              
Lock up period 2 years            
Unrealized (loss) gain on marketable equity securities     16,600,000   84,500,000    
Unrealized loss on investments       $ 13,200,000   $ 13,200,000  
Guardant Health AMEA, Inc | SoftBank              
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]              
Redeemable noncontrolling interest, redemption value   $ 41,000,000          
Fair Value, Measurements, Recurring              
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]              
Long-term marketable debt securities     102,804,000   102,804,000   $ 18,291,000
Contingent consideration     6,660,000   6,660,000   6,430,000
Level 1 | Fair Value, Measurements, Recurring              
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]              
Long-term marketable debt securities     102,804,000   102,804,000    
Contingent consideration     0   0   0
Level 1 | Fair Value, Measurements, Recurring | Lunit Inc.              
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]              
Long-term marketable debt securities     102,800,000   102,800,000   18,291,000
Level 3 | Fair Value, Measurements, Recurring              
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]              
Long-term marketable debt securities     0   0   0
Contingent consideration     6,660,000   6,660,000   6,430,000
Contingent consideration liability, noncurrent     $ 5,200,000   $ 5,200,000   $ 4,900,000