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Consolidated Balance Sheet Components (Tables)
12 Months Ended
Dec. 31, 2021
Balance Sheet Related Disclosures [Abstract]  
Property, Plant and Equipment
Estimated useful lives for property and equipment are as follows:
Property and EquipmentEstimated Useful Life
Machinery and equipment
3 – 5 years
Furniture and fixtures
7 years
Computer hardware and computer software
3 years
Leasehold improvementsLesser of estimated useful life or remaining lease term
Property and equipment, net consist of the following:
As of December 31,
20212020
(in thousands)
Machinery and equipment
$63,022 $40,216 
Leasehold improvements
38,702 34,037 
Computer hardware
16,685 10,862 
Construction in progress(1)
55,873 7,833 
Furniture and fixtures
3,683 3,043 
Computer software
1,320 1,136 
Property and equipment, gross
$179,285 $97,127 
Less: accumulated depreciation
(54,824)(34,345)
Property and equipment, net
$124,461 $62,782 
(1)    Under construction in progress, $45.8 million and $1.1 million was related to leasehold improvements, furniture and equipment for the office in Palo Alto, California, as of December 31, 2021 and 2020, respectively.
Schedule of Accrued Liabilities
Accrued expenses consist of the following:
As of December 31,
20212020
(in thousands)
Operating lease liabilities
$12,856 $6,632 
Accrued tax liabilities
4,223 4,634 
Accrued professional services
6,994 3,397 
Accrued clinical studies
3,332 1,264 
Accrued legal expenses
4,166 2,875 
Purchases of property and equipment included in accrued expenses
5,893 1,156 
Others
7,821 2,681 
Total accrued expenses
$45,285 $22,639