Accrued Liabilities and Other Liabilities - Summary (Details) - USD ($) $ in Thousands	Sep. 30, 2023	Dec. 31, 2022
Accrued liabilities:
Accrued clinical expense	$ 35,184	$ 37,604
Accrued manufacturing expense	5,310	6,605
Accrued development expense	5,006	20,107
Accrued compensation and benefits	34,495	40,208
Accrued commercial expense	2,920	3,941
Accrued royalty expense	1,187	0
Accrued adjustments to product revenue	2,772	152
Other accrued expenses	4,524	4,126
Lease liability (current)	8,020	7,844
Total accrued liabilities	99,418	120,587
Other liabilities	$ 3,661	$ 3,022