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                          February 24, 2021

       Ofer Haviv
       President and Chief Executive Officer
       Evogene Ltd.
       13 Gad Feinstein Street, Park Rehovot, Rehovot
       P.O. Box 4173, Ness Ziona 7414003, Israel

                                                        Re: Evogene Ltd.
                                                            Registration
Statement on Form F-3
                                                            Filed February 19,
2021
                                                            File No. 333-253300

       Dear Mr. Haviv:

              This is to advise you that we have not reviewed and will not
review your registration
       statement.

               Please refer to Rules 460 and 461 regarding requests for
acceleration. We remind you
       that the company and its management are responsible for the accuracy and
adequacy of their
       disclosures, notwithstanding any review, comments, action or absence of
action by the staff.

                                                        Please contact Jason
Drory at 202-551-8342 with any questions.




                          Sincerely,


                          Division of Corporation Finance

                          Office of Life Sciences
       cc:                                              Oded Har-Even, Esq.