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Summary of Reconciliation of Expected Income Tax Benefit Computed Using Federal Statutory Income Tax Rate To Company's Effective Income Tax Rate (Details)
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Income Tax Disclosure [Abstract]    
Income tax computed at federal statutory tax rate 21.00% 21.00%
State taxes, net of federal benefit 5.00% 3.10%
Research and development credits 1.80% 2.60%
Expiration of stock options (0.30%) (2.30%)
Write-down of goodwill assets (3.70%)
Non-deductible warrant inducement (10.10%)
Permanent differences (0.30%) (0.40%)
Limitations on credits and net operating losses (16.30%) (5.30%)
Other (0.80%)
Change in valuation allowance (7.20%) (7.80%)
Total