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Summary of Significant Accounting Policies - Additional Information (Detail)
12 Months Ended
Aug. 16, 2022
Aug. 09, 2022
Dec. 31, 2022
USD ($)
Segment
Dec. 31, 2021
USD ($)
Dec. 31, 2020
USD ($)
shares
Dec. 31, 2019
shares
Significant Accounting Policies [Line Items]            
Number of operating segments | Segment     1      
Maturity of highly liquid investments     3 months      
Maturity of certificates of deposit, commercial paper, corporate notes and corporate bonds     more than three months      
Impairment losses recognized     $ 0      
Assumed expected dividend rate     0.00% 0.00% 0.00%  
Average Annual Adjusted Income     $ 1,000,000,000      
Percentage Of Provision For Corporate Alternative Minimum Tax Rate 15.00% 25.00%        
CAPLYTA [Member]            
Significant Accounting Policies [Line Items]            
Advertising costs     $ 85,800,000 $ 82,500,000 $ 36,300,000  
Customer one [Member] | Accounts Receivable [Member] | Customer Concentration Risk [Member]            
Significant Accounting Policies [Line Items]            
Concentration Risk, Percentage     39.00% 40.00%    
Customer two [Member] | Accounts Receivable [Member] | Customer Concentration Risk [Member]            
Significant Accounting Policies [Line Items]            
Concentration Risk, Percentage     30.00% 28.00%    
Customer three [Member] | Accounts Receivable [Member] | Customer Concentration Risk [Member]            
Significant Accounting Policies [Line Items]            
Concentration Risk, Percentage     28.00% 28.00%    
2018 Equity Incentive Plan [Member]            
Significant Accounting Policies [Line Items]            
Additional shares of common stock reserved for future equity grants | shares         6,500,000  
Minimum [Member]            
Significant Accounting Policies [Line Items]            
Property and equipment, estimated useful life     3 years      
Minimum [Member] | Product [Member] | Bristol Myers Squibb Company [Member]            
Significant Accounting Policies [Line Items]            
Royalty Payment Percentage     5.00%      
Maximum [Member]            
Significant Accounting Policies [Line Items]            
Property and equipment, estimated useful life     5 years      
Maximum [Member] | Product [Member] | Bristol Myers Squibb Company [Member]            
Significant Accounting Policies [Line Items]            
Royalty Payment Percentage     9.00%      
Maximum [Member] | Accounts Receivable [Member] | Customer Concentration Risk [Member]            
Significant Accounting Policies [Line Items]            
Concentration Risk, Percentage     97.00% 96.00%    
Maximum [Member] | Inducement Award Plan [Member]            
Significant Accounting Policies [Line Items]            
Issuance of shares, Inducement Award Plan | shares           1,000,000