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Share-Based Compensation - Additional Information (Detail) - USD ($)
12 Months Ended
Dec. 31, 2015
Dec. 31, 2014
Dec. 31, 2013
Jan. 31, 2015
Jan. 31, 2014
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Purchase of common stock 2,737,657 2,233,460      
Options, maximum term 10 years        
Weighted-average grant date fair value for awards granted $ 21.00 $ 16.50 $ 3.26    
Total intrinsic value of the options exercised $ 10,951,057 $ 3,696,775 $ 580,623    
Total fair value of shares vested $ 5,207,073 $ 3,703,000 $ 278,000    
Options granted, Number of Shares 884,703        
Options granted, exercise price $ 21.00        
Unrecognized share-based compensation expense related to employee stock option awards $ 12,733,859        
Stock Options [Member]          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Unrecognized share-based compensation expense, weighted-average recognition period 1 year 7 months 6 days        
Scientific Advisory Board Members [Member]          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Options granted, Number of Shares 45,571 95,000 19,000    
Options granted, exercise price $ 17.57 $ 16.86 $ 3.26    
2013 Equity Incentive Plan [Member]          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Purchase of common stock 2,737,657        
Shares of common stock reserved for issuance 2,850,000     800,000 800,000
Number of shares of common stock available for issuance under the plan 3,100,000        
Increase in maximum number of shares available for issuance of options, stock appreciation rights and other similar awards 100,000        
Minimum [Member]          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Incentive stock options (ISOs), vesting period 2 years        
Minimum [Member] | Scientific Advisory Board Members [Member]          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Incentive stock options (ISOs), vesting period 12 months        
Maximum [Member]          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Incentive stock options (ISOs), vesting period 3 years        
Maximum [Member] | Scientific Advisory Board Members [Member]          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Incentive stock options (ISOs), vesting period 24 months