Exhibit 4.1

Iroko Pharmaceuticals Inc. INCORPORATED UNDER THE LAWSOF THE BRITISH VIRGIN ISLANDS CUSIP G49497 10 3 SEE REVERSE FOR CERTAIN DEFINITIONS IS THE RECORD HOLDER OF FULLY PAID AND NON-ASSESSABLE ORDINARY SHARES, $0.01 PAR VALUE, OFCOUNTERSIGNED AND REGISTERED:AMERICAN STOCK TRANSFER & TRUST COMPANY, LLC(Brooklyn, NY)TRANSFER AGENTAND REGISTRARBYAUTHORIZED SIGNATURE Iroko Pharmaceuticals Inc.Dated:CHIEF FINANCIAL OFFICERSEE REVERSE FOR CERTAIN DEFINITIONSCUSIP G49497 10 3INCORPORATED UNDER THE LAWSOF THE BRITISH VIRGIN ISLANDStransferable on the books of the Corporation by the holder hereof in person or by duly authorized Attorney, upon surrender of thisCertificate, properly endorsed.This Certificate is not valid until countersigned and registered by the Transfer Agent and Registrar.WITNESS the facsimile seal of the Corporation and the facsimile signatures of its duly authorized officers. PRESIDENT AND CHIEF EXECUTIVE OFFICER CHIEF FINANCIAL OFFICER

The following abbreviations, when used in the inscription on the face of this certificate, shall be construed as though they were written out in full according to applicablelaws or regulations:TEN COMTEN ENTJT TENas tenants in commonas tenants by the entiretiesas joint tenants with right ofsurvivorship and not as tenantsin commonAdditional abbreviations may also be used though not in the above list.–––represented by the within Certificate, and do hereby irrevocably constitute and appointto transfer the said ordinary shares on the books of the within named Corporation with full power of substitution in the premises.Dated For Value Received, hereby sell, assign and transfer untoPLEASE INSERT SOCIAL SECURITY OR OTHERIDENTIFYING NUMBER OF ASSIGNEEOrdinary SharesAttorne UNIF GIFT MIN ACT – ..................Custodian..........................(Cust)(Minor)under Uniform Gifts to MinorsAct.............................................................. (State) NOTICE:Signature(s) THE SIGNATURE(S) TO THIS ASSIGNMENT MUST CORRESPOND WITH THE NAME(S) AS WRITTEN UPON THEFACE OF THE CERTIFICATE IN EVERY PARTICULAR, WITHOUT ALTERATION OR ENLARGEMENT OR ANYCHANGE WHATEVER.GuaranteedByTHE SIGNATURE(S) MUST BE GUARANTEED BY AN ELIGIBLE GUARANTOR INSTITUTION (BANKS,STOCKBROKERS, SAVINGS AND LOAN ASSOCIATIONS AND CREDIT UNIONS.WITH MEMBERSHIP IN ANAPPROVED SIGNATURE GUARANTEE MEDALLION PROGRAM), PURSUANT TO S.E.C. RULE 17Ad-15.