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Income Taxes - Summary of Effective Tax Rate Differs From Federal Statutory Tax Rate (Details)
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Income Tax Disclosure [Abstract]    
Federal statutory tax rate 21.00% 21.00%
Change in deferred tax asset valuation allowance (33.70%) (34.40%)
State taxes, net of federal benefit 1.90% 0.80%
Research and development tax credits 5.20% 5.60%
Stock-based compensation 6.90% 6.90%
Other (1.30%) 0.10%
Effective tax rate 0.00% 0.00%