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Net Loss per Share - Anti-dilutive shares (Details) - shares
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount 4,834,022 3,492,921
Warrants to purchase common stock    
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount 2,501,419 1,893,201
Options to purchase common stock    
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount 2,332,603 1,599,720