Leases

12 Months Ended

Dec. 31, 2021

Leases [Abstract]

Leases

7. Leases

The Company has non-cancelable operating leases for office and laboratory space in Malvern, Pennsylvania and Creve Coeur, Missouri which, as of December 31, 2021, have remaining lease terms of approximately 1.2 and 0.1 years, respectively. The discount rate used to account for the Company’s operating leases is the Company’s estimated incremental borrowing rate of 5.3%.

Supplemental balance sheet information related to leases was as follows:

	December 31,
	2021		2020
Operating Leases
Right-of-use lease assets	$	296	$	530
Lease liabilities, current		258		238
Lease liabilities, net of current portion		44		296
Total operating lease liabilities	$	302	$	534

The components of lease expense were as follows:

	Year ended December 31,
	2021		2020
Operating lease costs
Operating lease rental expense	$	303	$	262
Interest on lease liabilities		22		35
Total operating lease expense	$	325	$	297

Supplemental cash flow information related to leases was as follows:

	Year ended December 31,
	2021		2020
Cash paid for amounts included in the measurement of lease liabilities
Operating cash flows for operating leases	$	325	$	445
Right-of-use assets obtained in exchange for lease obligation
Operating leases		70		—

Our operating lease liabilities as of December 31, 2021 will mature, as follows (amounts in thousands):

2022	$	266
2023		44
Total		310
Less: imputed interest		(8	)
	$	302