SEC FORM 3

SEC Form 3

FORM 3

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person^*

Nguyen Anhco T.

(Last)

(First)

(Middle)

C/O ENUMERAL BIOMEDICAL HOLDINGS, INC.,

200 CAMBRIDGE PARK DRIVE, SUITE 2000

(Street)

CAMBRIDGE

02140

(City)

(State)

(Zip)

2. Date of Event Requiring Statement (Month/Day/Year)
04/03/2015

3. Issuer Name and Ticker or Trading Symbol
Enumeral Biomedical Holdings, Inc. [ ENUM ]

4. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

	Director	10% Owner
X	Officer (give title below)	Other (specify below)
	VP of Research and Development

5. If Amendment, Date of Original Filed (Month/Day/Year)

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Beneficially Owned
1. Title of Security (Instr. 4)	2. Amount of Securities Beneficially Owned (Instr. 4)	3. Ownership Form: Direct (D) or Indirect (I) (Instr. 5)	4. Nature of Indirect Beneficial Ownership (Instr. 5)
Common Stock	0	D

Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 4)	2. Date Exercisable and Expiration Date (Month/Day/Year)		3. Title and Amount of Securities Underlying Derivative Security (Instr. 4)		4. Conversion or Exercise Price of Derivative Security	5. Ownership Form: Direct (D) or Indirect (I) (Instr. 5)	6. Nature of Indirect Beneficial Ownership (Instr. 5)
1. Title of Derivative Security (Instr. 4)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares	4. Conversion or Exercise Price of Derivative Security	5. Ownership Form: Direct (D) or Indirect (I) (Instr. 5)	6. Nature of Indirect Beneficial Ownership (Instr. 5)
Employee Stock Option (Right to Buy)	⁽¹⁾	07/30/2024	Common Stock	90,000	$1	D
Employee Stock Option (Right to Buy)	⁽²⁾⁽⁶⁾	07/17/2024	Common Stock	28,655	$1	D
Employee Stock Option (Right to Buy)	⁽³⁾⁽⁶⁾	07/25/2023	Common Stock	49,595	$0.245	D
Employee Stock Option (Right to Buy)	⁽⁴⁾⁽⁶⁾	10/26/2022	Common Stock	35,819	$0.245	D
Employee Stock Option (Right to Buy)	⁽⁵⁾⁽⁶⁾	10/26/2022	Common Stock	35,819	$0.245	D

Explanation of Responses:

1. The option vests and becomes exercisable as follows: (a) 15,000 shares will vest in 48 equal monthly installments beginning on July 31, 2014, and (b) 75,000 shares will vest upon the achievement of certain performance criteria.

2. The option vests and becomes exercisable in 48 equal monthly installments beginning on July 25, 2013.

3. The option vests and becomes exercisable upon the achievement of certain performance criteria.

4. The option vests and becomes exercisable as follows: (a) as to 23,878 shares, in 48 equal monthly installments beginning on November 26, 2012; and (b) as to 11,941 shares, upon the achievement of certain performance criteria.

5. The option vests and becomes exercisable as follows: (a) 3,857 shares on October 26, 2012; (b) 5,511 shares on January 4, 2013; (c) as to 16,532 shares, in 36 equal monthly installments beginning on February 4, 2013; and (d) as to 9,919 shares, upon the achievement of certain performance criteria.

6. Represents an option issued to the reporting person in exchange for an option previously issued by Enumeral Biomedical Corp. (the "Predecessor") pursuant to the terms of the merger of the Predecessor with a wholly-owned subsidiary of the Issuer.

	/s/ Anhco Nguyen	04/03/2015
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 5 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
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