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Net Income (Loss) Per Ordinary Share (Tables)
3 Months Ended
Mar. 31, 2024
Earnings Per Share [Abstract]  
Calculation of Basic and Diluted Net Income (Loss) Per Ordinary Share
Net income (loss) per ordinary share was determined as follows (in thousands, except per share amounts):
Three Months Ended 
March 31,
20242023
Numerator:
Net loss
$(72,239)$(46,864)
Denominator:
Weighted-average ordinary shares outstanding used in per share calculations - basic53,714 52,501 
Weighted-average ordinary shares outstanding used in per share calculations - diluted53,714 52,501 
Net income (loss) per share:
Basic net income (loss) per ordinary share
$(1.34)$(0.89)
Diluted net income (loss) per ordinary share
$(1.34)$(0.89)
Ordinary Shares Equivalent Not Included in Diluted Net Income (Loss) Per Ordinary Share
The equivalent ordinary shares not included in diluted net income (loss) per share because their effect would be anti-dilutive are as follows (in thousands):
 Three Months Ended 
March 31,
20242023
Stock options to purchase ordinary shares11,751 10,471 
Restricted Stock Units (RSU)25 23 
Total11,776 10,494