Significant Agreements - Roche License Agreement (Details) - USD ($) $ in Thousands		1 Months Ended			3 Months Ended		6 Months Ended
	May 05, 2021	Jun. 30, 2017	May 31, 2014	Feb. 28, 2014	Jun. 30, 2023	Jun. 30, 2022	Jun. 30, 2023	Jun. 30, 2022	Dec. 31, 2022
License Agreement [Line Items]
Accounts receivable					$ 524		$ 524		$ 0
Collaboration revenue					4,019	$ 1,312	$ 6,188	$ 2,465
Collaborative Arrangement
License Agreement [Line Items]
Portion of revenue and expenses attributable to company, Percentage							30.00%
Roche
License Agreement [Line Items]
Milestone achievement, Clinical milestone	$ 60,000
Revenue, Remaining performance obligation, Amount					0		$ 0		$ 0
Roche | Collaborative Arrangement
License Agreement [Line Items]
Collaboration revenue, License, Upfront payment				$ 30,000
Milestone payment received, Clinical milestone			$ 15,000
Milestone achievement, Clinical milestone		$ 30,000
Potential payment upon achievement of development, regulatory and various first commercial sales milestones							290,000
Potential payment for achievement of non U.S. commercial sales milestones							$ 175,000
Portion of revenue and expenses attributable to company, Percentage							70.00%
Potential alternative commercial sales milestones							$ 155,000
License agreement, Cost allocation, Percentage							100.00%
Collaboration revenue
License Agreement [Line Items]
Collaboration revenue					$ 4,019	$ 1,312	$ 6,138	$ 2,415