Condensed Consolidated Statements of Operations - USD ($) shares in Thousands, $ in Thousands	3 Months Ended
	Mar. 31, 2023	Mar. 31, 2022
Total revenue	$ 2,169	$ 1,153
Operating expenses:
Research and development	44,756	27,262
General and administrative	13,738	11,835
Total operating expenses	58,494	39,097
Loss from operations	(56,325)	(37,944)
Other income (expense):
Interest income	6,690	53
Other expense, net	(141)	(70)
Total other income (expense), net	6,549	(17)
Loss before income taxes	(49,776)	(37,961)
Benefit from income taxes	(2,912)	(1,671)
Net loss	$ (46,864)	$ (36,290)
Basic (in dollars per share)	$ (0.89)	$ (0.78)
Diluted (in dollars per share)	$ (0.89)	$ (0.78)
Weighted-average ordinary shares outstanding used in per share calculations- basic (in shares)	52,501	46,704
Weighted-average ordinary shares outstanding used in per share calculations- diluted (in shares)	52,501	46,704
Collaboration revenue
Total revenue	$ 2,119	$ 1,103
Revenue from license and intellectual property
Total revenue	$ 50	$ 50