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Share-Based Compensation - Summary of Share-Based Compensation Expense (Details) - USD ($)
$ in Thousands
3 Months Ended
Mar. 31, 2022
Mar. 31, 2021
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]    
Share-based compensation expense $ 7,660 $ 6,176
Share-based compensation cost not yet recognized, Stock Options $ 83,600  
Expected recognition period of share-based compensation not yet recognized 2 years 10 months 24 days  
Research and development    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]    
Share-based compensation expense $ 3,311 1,954
General and administrative    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]    
Share-based compensation expense $ 4,349 $ 4,222