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Net Income (Loss) Per Ordinary Share - Calculation of Basic and Diluted Net Income or Loss Per Share (Details) - USD ($)
$ / shares in Units, shares in Thousands, $ in Thousands
3 Months Ended
Mar. 31, 2016
Mar. 31, 2015
Numerator:    
Net loss $ (27,521) $ (15,202)
Denominator:    
Weighted-average ordinary shares outstanding (in shares) 34,026 27,401
Net loss per share:    
Basic and diluted net loss per share (in dollars per share) $ (0.81) $ (0.55)