CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021	Dec. 31, 2020
Cash flows from operating activities:
Net loss	$ (86,908)	$ (90,865)	$ (51,015)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation and amortization	797	923	1,324
Stock-based compensation expense	15,039	14,060	11,207
Revaluation of contingent consideration	4,700	24,339	2,393
Loss on extinguishment of debt		752
Deferred taxes			(182)
Changes in operating assets and liabilities:
Accounts receivable	139	149	4,898
Prepaid expenses and other assets	(2,294)	(5,617)	1,689
Accounts payable	368	3,655	(5,219)
Accrued expenses	592	470	(3,728)
Net cash used in operating activities	(67,567)	(52,134)	(38,633)
Cash flows from investing activities:
Purchases of property and equipment	(605)	(308)	(453)
Purchases of marketable securities	(164,753)	(235,153)	(47,714)
Proceeds from sales and maturities of marketable securities	177,986	67,829	54,554
Net cash provided by (used in) investing activities	12,628	(167,632)	6,387
Cash flows from financing activities:
Proceeds from debt financing (including warrants), net of issuance costs			10,913
Repayment of debt		(11,483)
Payments of employee withholding taxes related to restricted stock unit award vesting	(34)	(3,124)
Finance lease payments			(137)
Deferred issuance costs			(211)
Proceeds from exercise of employee stock options and the issuance of stock	157	1,459	70
Net cash provided by financing activities	72,867	225,052	18,372
Net increase (decrease) in cash and cash equivalents	17,928	5,286	(13,874)
Cash and cash equivalents at beginning of period	27,349	22,063	35,937
Cash and cash equivalents at end of period	45,277	27,349	22,063
Supplemental disclosure of non-cash investing and financing activities:
Additions to property and equipment included in accounts payable	24	143
Fair value of warrants issued in connection with debt financing			378
Fair value of common stock issued in connection with an equity purchase agreement			263
Equity Purchase Agreement
Cash flows from financing activities:
Proceeds from issuance of common stock, net of issuance costs			$ 7,737
Public Offering
Cash flows from financing activities:
Proceeds from issuance of common stock, net of issuance costs		$ 238,200
At The Market Offering
Cash flows from financing activities:
Proceeds from issuance of common stock, net of issuance costs	$ 72,744