Exhibit 1

JOINT FILING AGREEMENT

In accordance with Rule 13d-1(k)(1) promulgated under the Securities Exchange Act of 1934, as amended, the undersigned hereby agree that they are jointly filing this statement on Schedule 13G. Each of them is responsible for the timely filing of such statement and any amendments thereto, and for the completeness and accuracy of the information concerning such person contained therein; but none of them is responsible for the completeness or accuracy of the information concerning the other persons making the filing, unless such person knows or has reason to believe that such information is inaccurate.

IN WITNESS WHEREOF, the undersigned hereby execute this Joint Filing Agreement as of the 15^th day of December, 2020.

Ally Bridge MedAlpha Master Fund L.P.
By: Ally Bridge MedAlpha General Partner L.P., its general partner
By: Ally Bridge MedAlpha GP, LLC, its general partner
By:	/s/ Fan Yu
Name:	Fan Yu
Title:	Manager
Ally Bridge MedAlpha Management L.P.
By: Ally Bridge MedAlpha Management GP, LLC, its general partner
By: ABG Management Ltd., its managing member
By:	/s/ Fan Yu
Name:	Fan Yu
Title:	Director
Ally Bridge MedAlpha Management GP, LLC
By: ABG Management Ltd., its managing member
By:	/s/ Fan Yu
Name:	Fan Yu
Title:	Director
Ally Bridge Group (NY) LLC
By: ABG Management Ltd., its managing member
By:	/s/ Fan Yu
Name:	Fan Yu
Title:	Director

ABG Management Ltd.
By:	/s/ Fan Yu
Name:	Fan Yu
Title:	Director
Fan Yu
/s/ Fan Yu
Name: Fan Yu