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Revenue - Revenue by Product (Details) - USD ($)
$ in Millions
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Revenue from External Customer [Line Items]      
Revenues $ 7,776 $ 6,675 $ 6,260
Vaccines      
Revenue from External Customer [Line Items]      
Revenues 1,673 1,476 1,483
Other pharmaceuticals      
Revenue from External Customer [Line Items]      
Revenues 966 821 780
Dermatology [Member]      
Revenue from External Customer [Line Items]      
Revenues 1,180 941 770
Anti-infectives      
Revenue from External Customer [Line Items]      
Revenues 1,215 1,206 1,254
Parasiticides      
Revenue from External Customer [Line Items]      
Revenues 1,635 1,173 966
Other non-pharmaceuticals      
Revenue from External Customer [Line Items]      
Revenues 231 210 184
Medicated feed additives      
Revenue from External Customer [Line Items]      
Revenues 420 460 470
Animal health diagnostics      
Revenue from External Customer [Line Items]      
Revenues 374 305 268
Total Products and Services      
Revenue from External Customer [Line Items]      
Revenues 7,694 6,592 6,175
Contract Manufacturing and Human Health Diagnostics [Member]      
Revenue from External Customer [Line Items]      
Revenues $ 82 $ 83 $ 85