Exhibit 15

ACCOUNTANTS’ ACKNOWLEDGEMENT

To the Shareholders and Board of Directors

Zoetis Inc.:

We hereby acknowledge our awareness of the use therein of our report dated August 8, 2017, included within the Quarterly Report on Form 10-Q of Zoetis Inc. for the quarter ended July 2, 2017, in the following Registration Statements:

• Form S-8, dated February 1, 2013, (File No. 333-186367),

• Form S-8, dated June 25, 2013, (File No. 333-189573),

• Form S-8, dated November 10, 2014, (File No. 333-200073), and

• Form S-3, dated July 21, 2015, (File No. 333-205777).

Pursuant to Rule 436 under the Securities Act of 1933 (the Act), such report is not considered a part of a registration statement prepared or certified by an independent registered public accounting firm, or a report prepared or certified by an independent registered public accounting firm within the meaning of Sections 7 and 11 of the Act.

/s/ KPMG LLP

Short Hills, New Jersey

August 8, 2017