MORGAN STANLEY & CO. LLC	MERRILL LYNCH, PIERCE, FENNER &
1585 Broadway	SMITH INCORPORATED
New York, New York 10036	One Bryant Park
	New York, New York 10036

January 15, 2013

VIA EDGAR

U.S. Securities and Exchange Commission

Division of Corporation Finance

100 F. Street, N.E.

Washington, D.C. 20549

Attention:	Ms. Jennifer Gowetski, Senior Counsel
	Ms. Kristi Marrone, Staff Accountant
	Mr. Daniel Gordon, Accounting Branch Chief
	Ms. Folake Ayoola, Attorney Advisor
	Re:	CyrusOne Inc.
		Registration Statement on Form S-11
		File No. 333-183132
		Acceleration Request

Ladies and Gentlemen:

As representatives of the several underwriters of the proposed public offering of 16,500,000 shares of common stock of CyrusOne Inc. (the “Company”), we hereby join the Company’s request to accelerate the date of the above-referenced Registration Statement, as then amended, effective as of 3 p.m. (Washington, D.C. time) on January 17, 2013, or as soon thereafter as is practicable.

Pursuant to Rule 460 under the Securities Act of 1933, as amended, we wish to advise you that we have effected the following distribution of the Company’s preliminary prospectus, dated January 8, 2013, through the date hereof: approximately 4,670 copies to prospective underwriters, institutional investors, dealers and others.

The undersigned have been informed by the participating underwriters that they have complied and will continue to comply with Rule 15c2-8 under the Securities Exchange Act of 1934, as amended.

(Signature Page Follows)

Very truly yours,
MORGAN STANLEY & CO. LLC
MERRILL LYNCH, PIERCE, FENNER & SMITH                                INCORPORATED
As representatives of the several underwriters
By MORGAN STANLEY & CO. LLC
By:	/s/ Tom Boyle
	Authorized Representative
	Tom Boyle
	Vice President
By MERRILL LYNCH, PIERCE, FENNER & SMITH                                     INCORPORATED
By:	/s/ Michele A. H. Allong
	Authorized Representative
	MICHELE A. H. ALLONG AUTHORIZED SIGNATORY