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Collaboration and License Revenue - Changes in Contract Assets and Liabilities (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2018
Dec. 31, 2017
Contract liabilities:    
Deferred revenue, Balance at Beginning of Period $ 33,558  
Deferred revenue, Deductions $ (33,558) $ (11,442)
Deferred revenue, Balance at End of Period   $ 33,558