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Condensed Consolidated Statements of Operations and Comprehensive Loss (Unaudited) - USD ($)
$ in Thousands
3 Months Ended
Mar. 31, 2019
Mar. 31, 2018
Income Statement [Abstract]    
Collaboration and license revenue   $ 5,331
Operating expenses:    
Research and development $ 26,190 16,618
General and administrative 13,551 7,313
Total operating expenses 39,741 23,931
Loss from operations (39,741) (18,600)
Interest and other income, net 2,271 780
Net loss (37,470) (17,820)
Other comprehensive gain (loss) 363 (137)
Comprehensive loss $ (37,107) $ (17,957)
Net loss per share, basic and diluted $ (0.93) $ (0.50)
Weighted average number of shares used to compute net loss per share, basic and diluted 40,506,313 35,827,235