Income Taxes - Provision for Income Taxes Differs Amount Expected by Applying the Federal Statutory Rate Loss Before Taxes (Details)	12 Months Ended
Dec. 31, 2016	Dec. 31, 2015
Income Tax Disclosure [Abstract]
Federal statutory income tax rate	34.00%	34.00%
State taxes (tax effected)	7.87%	7.19%
Non-deductible expenses and other	(10.19%)
Research and development credits	14.07%	2.98%
Change in valuation allowance	(45.75%)	(44.17%)
Total	0.00%	0.00%

Percentage of current income tax expense (benefit) and deferred income tax expense (benefit) pertaining to continuing operations.

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-Publisher FASB
-Name Accounting Standards Codification
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-Section 50
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Percentage of domestic federal statutory tax rate applicable to pretax income (loss).

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Percentage of the difference between reported income tax expense (benefit) and expected income tax expense (benefit) computed by applying the domestic federal statutory income tax rates to pretax income (loss) from continuing operations attributable to changes in the valuation allowance for deferred tax assets.

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Percentage of the difference between reported income tax expense (benefit) and expected income tax expense (benefit) computed by applying the domestic federal statutory income tax rates to pretax income (loss) from continuing operations applicable to state and local income tax expense (benefit), net of federal tax expense (benefit).

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