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Stock-Based Compensation (Tables)
9 Months Ended
Sep. 30, 2016
Disclosure Of Compensation Related Costs Sharebased Payments [Abstract]  
Schedule of Stock-Based Compensation Expense Related to Options Granted to Employees and Consultants

The following table sets forth stock-based compensation expense related to options granted to employees and consultants for all periods presented (in thousands):

 

 

Three Months Ended

September 30,

 

 

Nine Months Ended

September 30,

 

 

2016

 

 

2015

 

 

2016

 

 

2015

 

Research and development

$

269

 

 

$

29

 

 

$

690

 

 

$

79

 

General and administrative

 

494

 

 

 

113

 

 

 

1,091

 

 

 

167

 

Total

$

763

 

 

$

142

 

 

$

1,781

 

 

$

246

 

 

Summary of Stock Option Activity Under Plans

 

The following summarizes option activity under the 2012 Equity Incentive Plan and 2015 Stock Option and Incentive Plan:

 

 

 

Shares Subject to

 

 

Weighted Average

 

 

 

Outstanding Options

 

 

Exercise Price Per Share

 

Balance at December 31, 2015

 

 

1,318,647

 

 

 

2.29

 

Options granted

 

 

786,034

 

 

 

10.02

 

Options exercised

 

 

(18,913

)

 

 

0.71

 

Options canceled

 

 

(50,991

)

 

 

5.19

 

Balance at September 30, 2016

 

 

2,034,777

 

 

 

5.22