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Equity - Stock-Based Compensation (Details) - USD ($)
$ in Millions
3 Months Ended 6 Months Ended
Jun. 30, 2022
Jun. 30, 2021
Jun. 30, 2022
Jun. 30, 2021
Share-based Compensation Arrangement by Share-based Payment Award        
Pre-tax compensation expense $ 107 $ 159 $ 413 $ 428
Tax benefit 21 26 77 74
After-tax compensation expense 86 133 336 354
Cost of products sold        
Share-based Compensation Arrangement by Share-based Payment Award        
Pre-tax compensation expense 6 10 25 30
Research and development        
Share-based Compensation Arrangement by Share-based Payment Award        
Pre-tax compensation expense 40 47 147 134
Selling, general and administrative        
Share-based Compensation Arrangement by Share-based Payment Award        
Pre-tax compensation expense $ 61 $ 102 $ 241 $ 264