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Equity - Stock-Based Compensation (Details) - USD ($)
$ in Millions
12 Months Ended
Dec. 31, 2020
Dec. 31, 2019
Dec. 31, 2018
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Shares reserved for issuance (in shares) 100,000,000    
Retirement-eligible employees' age 55 years    
Minimum number of years of services 10 years    
Pre-tax compensation expense $ 753 $ 430 $ 421
Tax benefit 131 80 73
After-tax compensation expense 622 350 348
Realized excess tax benefits from the exercise of stock options 34 15 78
Cost of products sold      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Pre-tax compensation expense 47 29 27
Research and development      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Pre-tax compensation expense 247 171 169
Selling, general and administrative      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Pre-tax compensation expense $ 459 $ 230 $ 225