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Consolidated Statements of Operations - USD ($)
$ in Thousands
12 Months Ended
Nov. 30, 2021
Nov. 30, 2020
Nov. 30, 2019
Income Statement [Abstract]      
Collaboration revenue [1] $ 29,750 $ 17,820 $ 31,115
Operating expenses:      
Research and development 116,434 66,494 45,025
General and administrative 31,202 16,309 8,326
Total operating expenses 147,636 82,803 53,351
Loss from operations (117,886) (64,983) (22,236)
Interest and other income, net 823 1,206 776
Loss before income taxes (117,063) (63,777) (21,460)
Provision for (benefit from) income taxes 131 (20,535) 239
Net loss $ (117,194) $ (43,242) $ (21,699)
Net loss per share, basic and diluted $ (2.73) $ (2.76) $ (6.59)
Weighted-average number of shares outstanding, basic and diluted 42,895,383 15,673,424 3,292,514
[1]

Collaboration revenue for the years ended November 30, 2021, 2020 and 2019 includes related party revenue of $0, $0 and $28.4 million, respectively.