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Stock Compensation (Tables)
 9 Months Ended
Sep. 30, 2022
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]  
Schedule of Stock Based Compensation Expense Company’s Condensed Consolidated Statement of Operations for the three and nine months ended September 30, 2022:
Three Months Ended September 30,Nine Months Ended September 30,
2022202120222021
Research and development$148 $105 $375 $227 
General and administrative290 191 758 600 
Total$438 $296 $1,133 $827 
Summary of Information About Stock Options Outstanding
The following table summarizes information about stock options outstanding at September 30, 2022:

SharesWeighted Average Remaining Contractual Life (In Years)Weighted Average Exercise PriceAggregate Intrinsic Value
Options outstanding1,637,9298.78$8.72$—
Vested and expected to vest1,637,9298.78$8.72$—
Exercisable486,0897.71$15.22$—
Summary of Stock Options The following shows the stock option activities for the nine months ended September 30, 2022 and 2021:
Total Options OutstandingWeighted-Average Exercise Price
Balance—December 31, 2021790,637 $32.82 
Granted903,527 3.35 
Exercised— — 
Cancelled and forfeited(56,235)266.80 
Balance—September 30, 2022
1,637,929 8.72 
Balance—December 31, 2020452,165 $5.35 
Assumed in reverse recapitalization177,591 179.79 
Granted232,669 19.09 
Exercised(25,871)3.77 
Cancelled and forfeited(100,459)107.77 
Balance—September 30, 2021
736,095 37.47 
Share-based Payment Arrangement, Employee  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]  
Summary of Grant Date Fair Value The fair value of stock options was estimated using the following assumptions for the nine months ended September 30, 2022 and 2021:
20222021
Expected term (in years)
5.5 - 6.1
5.8 - 6.1
Expected volatility
110% - 112%
67% - 68%
Risk-free interest rate
1.5% - 3.4%
0.9% - 1.1%
Dividends
—%
—%