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Accrued expenses (Details) (USD $)
In Thousands, unless otherwise specified
Mar. 31, 2013
Dec. 31, 2012
Accrued expenses    
Professional and consultant fees $ 307 $ 441
Compensation and related benefits 370 471
License and patent fees 134 87
Market research and consulting 34 40
Contract research and clinical organizations 144 127
Travel and other expenses 157 45
Accrued expenses $ 1,146 $ 1,211