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Stock-based compensation (Details 2) (USD $)
3 Months Ended 12 Months Ended 24 Months Ended 3 Months Ended 24 Months Ended 3 Months Ended 24 Months Ended 3 Months Ended 0 Months Ended 3 Months Ended 24 Months Ended 3 Months Ended 0 Months Ended
Mar. 31, 2013
Stock options
Dec. 31, 2012
Stock options
Mar. 31, 2013
Stock options
Mar. 31, 2013
Stock options
Minimum
Mar. 31, 2012
Stock options
Minimum
Mar. 31, 2013
Stock options
Maximum
Mar. 31, 2012
Stock options
Maximum
Mar. 31, 2013
Stock options
Employees
Mar. 31, 2012
Stock options
Employees
Mar. 31, 2013
Stock options
Employees
Mar. 31, 2013
Stock options
Non-employees
Mar. 31, 2012
Stock options
Non-employees
Mar. 31, 2013
Stock options
Non-employees
Mar. 31, 2013
Restricted stock units
Dec. 05, 2012
Restricted stock units
CEO
Mar. 31, 2013
Restricted stock units
CEO
Mar. 31, 2013
Restricted stock units
CEO
Mar. 31, 2013
Time based restricted stock units
Dec. 05, 2012
Time based restricted stock units
CEO
Dec. 05, 2012
Performance based restricted stock units
CEO
Shares                                        
Outstanding at the beginning of the period (in shares) 1,218,153                                      
Granted (in shares) 437,542   1,774,111         437,542 60,799   12,356   205,024              
Exercised (in shares) (24,049)                                      
Outstanding at the end of the period (in shares) 1,631,646 1,218,153 1,631,646                                  
Exercisable at the end of the period (in shares) 227,503   227,503                                  
Vested and expected to vest at the end of the period (in shares) 1,487,084   1,487,084                                  
Weighted average exercise price per share                                        
Outstanding at the beginning of the period (in dollars per share) $ 3.83                                      
Granted (in dollars per share) $ 12.78             $ 12.78 $ 4.01     $ 4.01 $ 0.96              
Exercised (in dollars per share) $ 0.04                                      
Outstanding at the end of period (in dollars per share) $ 6.28 $ 3.83 $ 6.28                                  
Exercisable at the end of the period (in dollars per share) $ 1.55   $ 1.55                                  
Vested and expected to vest at the end of the period (in dollars per share) $ 6.22   $ 6.22                                  
Weighted average remaining contractual term                                        
Outstanding at the end of the period 9 years 3 months 22 days 9 years 3 months 25 days                                    
Exercisable at the end of the period 8 years 9 months                                      
Vested and expected to vest at the end of the period 8 years 9 months                                      
Outstanding at the end of the period 9 years 3 months 22 days 9 years 3 months 25 days                                    
Aggregate intrinsic value                                        
Outstanding at the end of period $ 5,535,000                                      
Exercisable at the end of period 1,694,000   1,694,000                                  
Vested and expected to vest at the end of the period 5,652,000   5,652,000                                  
Outstanding at the end of period 6,091,000 5,535,000 6,091,000                                  
Shares                                        
Unvested at the beginning of the period (in shares)                           192,308            
Granted (in shares)                             192,308       128,205 64,103
Vested (in shares)                           16,025   16,025        
Unvested at the end of the period (in shares)                           176,283            
Weighted-Average Grant Date Fair Value                                        
Unvested at the beginning of the period (in dollars per share)                           $ 8.80            
Granted (in dollars per share)                                     $ 7.80  
Vested (in dollars per share)                           $ 7.80            
Unvested at the end of the period (in dollars per share)                           $ 8.80            
Assumptions used to estimate fair value of each stock-based award on the grant date using the Black-Scholes option pricing model                                        
Risk free interest rate (as a percent)       0.90% 1.20% 1.10% 1.84%                          
Volatility (as a percent)       89.00% 79.00% 91.00% 82.00%                          
Expected term       5 years 3 months 18 days 6 years 9 years 8 months 12 days 9 years 9 months                          
Additional disclosures                                        
Weighted average grant-date fair value of options granted (in dollars per share)               $ 9.42 $ 2.84                      
Weighted average exercise price (in dollars per share)                               $ 0.001        
Stock-based compensation expense               342,000 44,000 688,000 363,000 215,000 1,362,000     132,000 168,000      
Total unrecognized compensation cost related to non-vested stock options and restricted stock (in dollars) $ 9,434,000   $ 9,434,000                             $ 1,525,000    
Weighted average period for recognition of compensation cost related to unvested stock awards 3 years 2 months 12 days                                 1 year 9 months 18 days    
Vested (in shares)                           16,025   16,025        
Future quarterly restricted stock unit award grant                                     16,025