Income Taxes (Details 3) (USD $)	12 Months Ended
Dec. 31, 2014	Dec. 31, 2013	Dec. 31, 2012
Reconciliation of income taxes computed using the U.S. federal statutory rate to that reflected in operations
Income tax benefit using U.S. federal statutory rate (as a percent)	34.00%	34.00%	34.00%
State income taxes, net of federal benefit (as a percent)	5.28%	5.28%	5.42%
Research and development tax credits (as a percent)	1.75%	0.00%	0.00%
Permanent items (as a percent)	(0.55%)	(1.09%)	(2.78%)
Foreign differential (as a percent)	(1.59%)
Other adjustments (state) (as a percent)	(0.03%)
Change in the valuation allowance (as a percent)	(38.86%)	(40.50%)	(36.64%)
Deferred tax assets:
Net operating loss carryforwards	$ 26,133,000	$ 12,939,000
Tax credit carryforwards	1,689,000	823,000
Accrued Expenses	655,000	190,000
Stock based compensation	5,591,000	1,602,000
Intangibles	2,536,000	1,954,000
Other	305,000us-gaap_DeferredTaxAssetsOther	160,000us-gaap_DeferredTaxAssetsOther
Gross deferred tax assets	36,909,000us-gaap_DeferredTaxAssetsGross	17,668,000us-gaap_DeferredTaxAssetsGross
Valuation allowance	(36,909,000)	(17,668,000)
Increase in valuation allowance	19,200,000	11,700,000
Unrecognized tax benefits	0us-gaap_UnrecognizedTaxBenefits	0us-gaap_UnrecognizedTaxBenefits
Interest and penalties accrued	0	0	0
Interest and penalties related to uncertain tax positions recognized	$ 0	$ 0	$ 0

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