The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP FIGI (to the nearest dollar) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ABBVIE INC Common Stock 00287Y109   336,589 2,112 SH   SOLE   336,589 0 0
ACADIA PHARMACEUTICALS INC Common Stock 004225108   308,272 16,380 SH   SOLE   308,272 0 0
ACTIVISION BLIZZARD INC Common Stock 00507V109   19,386,135 226,500 SH   SOLE   19,386,135 0 0
AGILENT TECHNOLOGIES INC Common Stock 00846U101   373,795 2,702 SH   SOLE   373,795 0 0
ALNYLAM PHARMACEUTICALS INC Common Stock 02043Q107   379,005 1,892 SH   SOLE   379,005 0 0
AMAZON.COM INC Common Stock 023135106   433,818 4,200 SH   SOLE   433,818 0 0
ARGENX SE - ADR ADR 04016X101   481,746 1,293 SH   SOLE   481,746 0 0
ASCENDIS PHARMA - ADR ADR 04351P101   249,287 2,325 SH   SOLE   249,287 0 0
ASTRAZENECA PLC-SPONS ADR ADR 046353108   693,059 9,985 SH   SOLE   693,059 0 0
BANCO BRADESCO-ADR ADR 059460303   115,280 44,000 SH   SOLE   115,280 0 0
BANCO MACRO SA-ADR ADR 05961W105   2,258,166 126,792 SH   SOLE   2,258,166 0 0
BECTON DICKINSON AND CO Common Stock 075887109   349,031 1,410 SH   SOLE   349,031 0 0
BEIGENE LTD-ADR ADR 07725L102   901,778 4,184 SH   SOLE   901,778 0 0
BIOMARIN PHARMACEUTICAL INC Common Stock 09061G101   263,812 2,713 SH   SOLE   263,812 0 0
CENTENE CORP Common Stock 15135B101   3,918,400 40,000 SH   SOLE   3,918,400 0 0
CENTRAIS ELETRICAS BR-SP ADR ADR 15234Q207   257,265 4,070 SH   SOLE   257,265 0 0
CIGNA CORP Common Stock 125523100   185,852 28,032 SH   SOLE   185,852 0 0
DANAHER CORP Common Stock 235851102   222,056 869 SH   SOLE   222,056 0 0
ELEVANCE HEALTH INC Common Stock 036752103   726,631 2,883 SH   SOLE   726,631 0 0
ELI LILLY & CO Common Stock 532457108   559,129 1,216 SH   SOLE   559,129 0 0
EXPEDIA INC Common Stock 30212P303   821,461 2,392 SH   SOLE   821,461 0 0
GRUPO FINANCIERO GALICIA-ADR ADR 399909100   291,090 3,000 SH   SOLE   291,090 0 0
HCA HOLDINGS INC Common Stock 40412C101   2,302,484 209,698 SH   SOLE   2,302,484 0 0
HUMANA INC Common Stock 444859102   204,088 774 SH   SOLE   204,088 0 0
INCYTE CORP Common Stock 45337C102   411,670 848 SH   SOLE   411,670 0 0
INTUITIVE SURGICAL INC Common Stock 46120E602   901,857 12,479 SH   SOLE   901,857 0 0
ISHARES EXPANDED TECH-SOFTWA ETP 464287515   560,501 2,194 SH   SOLE   560,501 0 0
ITAU UNIBANCO HLDNG-PREF ADR ADR 465562106   3,808,750 12,500 SH   SOLE   3,808,750 0 0
JD.COM INC-ADR ADR 47215P106   255,845 52,535 SH   SOLE   255,845 0 0
KRANESHARES CSI CHINA INTERN ETP 500767306   17,765,092 404,764 SH   SOLE   17,765,092 0 0
LOMA NEGRA CIA IND-SPON ADR ADR 54150E104   423,779 13,587 SH   SOLE   423,779 0 0
MARKET VECTORS GOLD MINERS ETP 92189F106   976,781 140,544 SH   SOLE   976,781 0 0
MERCK & CO. INC. Common Stock 58933Y105   218,654 6,759 SH   SOLE   218,654 0 0
MOLINA HEALTHCARE INC Common Stock 60855R100   671,853 6,315 SH   SOLE   671,853 0 0
OI SA-ADR ADR 670851500   249,033 931 SH   SOLE   249,033 0 0
PAMPA ENERGIA SA-SPON ADR ADR 697660207   2,070 575,000 SH   SOLE   2,070 0 0
PENUMBRA INC Common Stock 70975L107   1,109,777 33,650 SH   SOLE   1,109,777 0 0
PFIZER INC Common Stock 717081103   234,378 841 SH   SOLE   234,378 0 0
REGENERON PHARMACEUTICALS Common Stock 75886F107   357,367 8,759 SH   SOLE   357,367 0 0
S&P GLOBAL INC Common Stock 78409V104   685,273 834 SH   SOLE   685,273 0 0
SALESFORCE.COM INC Common Stock 79466L302   4,447,533 12,900 SH   SOLE   4,447,533 0 0
SBERBANK PJSC - SPONSORED ADR ADR 80585Y308   339,626 1,700 SH   SOLE   339,626 0 0
SEAGEN INC Common Stock 81181C104   7,248 160,000 SH   SOLE   7,248 0 0
SIGMA LITHIUM CORP Common Stock 826599102   3,565,092 17,608 SH   SOLE   3,565,092 0 0
STRYKER CORP Common Stock 863667101   5,238,961 139,260 SH   SOLE   5,238,961 0 0
THERMO FISHER SCIENTIFIC INC Common Stock 883556102   526,407 1,844 SH   SOLE   526,407 0 0
UNION PACIFIC CORP Common Stock 907818108   64 64,136 SH   SOLE   64 0 0
UNITEDHEALTH GROUP INC Common Stock 91324P102   1,103,749 1,915 SH   SOLE   1,103,749 0 0
VALOR LATITUDE ACQUISITION C Unit G9460N114   342,142 1,700 SH   SOLE   342,142 0 0
VERTEX PHARMACEUTICALS INC Common Stock 92532F100   1,510,398 3,196 SH   SOLE   1,510,398 0 0
WALT DISNEY CO/THE Common Stock 254687106   11,275,000 1,100,000 SH   SOLE   11,275,000 0 0
YPF S.A.-SPONSORED ADR ADR 984245100   480,797 1,526 SH   SOLE   480,797 0 0
ACTIVISION BLIZZARD INC Common Stock 00507V109   570,741 5,700 SH   SOLE   570,741 0 0
ACTIVISION BLIZZARD INC Common Stock 00507V109   1,228,662 111,900 SH   SOLE   1,228,662 0 0
ACTIVISION BLIZZARD INC Common Stock 00507V109   26,375 50 SH Call SOLE   26,375 0 0
ACTIVISION BLIZZARD INC Common Stock 00507V109   63,150 300 SH Put SOLE   63,150 0 0
ACTIVISION BLIZZARD INC Common Stock 00507V109   19,400 40 SH Call SOLE   19,400 0 0
ALIBABA GROUP HOLDING-SP ADR ADR 01609W102   34,750 100 SH Call SOLE   34,750 0 0
ALIBABA GROUP HOLDING-SP ADR ADR 01609W102   107,000 2,000 SH Put SOLE   107,000 0 0
DEUTSCHE BANK AG-REGISTERED Common Stock D18190898   6,250 500 SH Put SOLE   6,250 0 0
ALPHABET INC-CL C Common Stock 02079K107   39,500 50 SH Call SOLE   39,500 0 0
JD.COM INC-ADR ADR 47215P106   3,485 85 SH Call SOLE   3,485 0 0
JD.COM INC-ADR ADR 47215P106   7,607 85 SH Put SOLE   7,607 0 0
NVIDIA CORP Common Stock 67066G104   121,000 2,000 SH Put SOLE   121,000 0 0
SCHWAB (CHARLES) CORP Common Stock 808513105   665 190 SH Call SOLE   665 0 0
SIGMA LITHIUM CORP Common Stock 826599102   480,000 2,000 SH Put SOLE   480,000 0 0
SIGMA LITHIUM CORP Common Stock 826599102   202,500 3,000 SH Put SOLE   202,500 0 0