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Schedule of Fair Value of Warrants (Details) - $ / shares
3 Months Ended 12 Months Ended
Mar. 31, 2022
Mar. 31, 2021
Dec. 31, 2021
Subsidiary, Sale of Stock [Line Items]      
Expected life in years 5 years 10 months 6 days 5 years 10 months 6 days  
Risk-free interest rate 1.41% 0.47%  
Dividend yield 0.00% 0.00%  
Volatility 102.43% 100.96%  
Warrant [Member]      
Subsidiary, Sale of Stock [Line Items]      
Expected life in years 2 years 7 months 17 days   2 years 10 months 17 days
Risk-free interest rate 2.64%   0.97%
Volatility 100.00%   100.00%
Stock price $ 1.38   $ 0.99
November 2019 Offering [Member] | Fair Value, Inputs, Level 3 [Member] | Warrant [Member]      
Subsidiary, Sale of Stock [Line Items]      
Expected life in years 2 years 7 months 17 days   2 years 10 months 17 days
Risk-free interest rate 2.64%   0.97%
Dividend yield  
Volatility 100.00%   100.00%
Stock price $ 1.38   $ 0.99