Consolidated Statements of Changes in Stockholders' Equity - USD ($)	Common Stock [Member]	Treasury Stock [Member]	Additional Paid-in Capital [Member]	AOCI Attributable to Parent [Member]	Retained Earnings [Member]	Total
Beginning balance, value at Dec. 31, 2019	$ 3,766	$ (40,712)	$ 157,391,969	$ (38)	$ (151,067,189)	$ 6,287,796
Balance, shares at Dec. 31, 2019	37,649,465	5,710
Net loss					(20,964,819)	(20,964,819)
Unrealized net loss on marketable investment securities				38		38
Common stock sold through equity offering	$ 1,008		5,652,132			5,653,140
Common stock sold through equity offering, shares	10,084,034
Common stock issued for warrant exercises	$ 1,510		7,673,366			7,674,876
Common stock issued for warrant exercises, shares	15,097,651
Stock-based compensation			1,373,182			1,373,182
Settlement of warrant liability on warrant exercises			6,313,338			6,313,338
Vesting of restricted stock units	$ 63		(63)
Vesting of restricted stock units, shares	628,807
Common stock sold through ATM offering	$ 658		9,003,710			9,004,368
Common stock sold through ATM offering, shares	6,576,300
Ending balance, value at Dec. 31, 2020	$ 7,005	$ (40,712)	187,407,634		(172,032,008)	15,341,919
Balance, shares at Dec. 31, 2020	70,036,257	5,710
Net loss					(634,399)	(634,399)
Unrealized net loss on marketable investment securities				(18,016)		(18,016)
Common stock sold through equity offering	$ 1,643		26,838,814			26,840,457
Common stock sold through equity offering, shares	16,428,571
Common stock issued for warrant exercises	$ 1		4,999			5,000
Common stock issued for warrant exercises, shares	10,000
Stock-based compensation			603,946			603,946
Settlement of warrant liability on warrant exercises			18,365			18,365
Common stock sold through ATM offering	$ 181		3,405,872			3,406,053
Common stock sold through ATM offering, shares	1,811,238
Option exercises			6,693			6,693
Option exercises, shares	4,584
Ending balance, value at Dec. 31, 2021	$ 8,830	$ (40,712)	$ 218,286,323	$ (18,016)	$ (172,666,407)	$ 45,570,018
Balance, shares at Dec. 31, 2021	88,290,650	5,710