Income Taxes (Details 2) - USD ($)	Dec. 31, 2019	Dec. 31, 2018
Deferred tax assets:
Stock-based compensation	$ 1,637,731	$ 1,540,215
Net operating loss carryforwards	30,574,751	27,397,503
Employee benefits	48,423	48,294
Research and development tax credits	3,833,189	3,362,473
Orphan drug tax credits	1,162,757	1,144,583
Plant and equipment	1,782	234
Other deductible temporary differences	5,806	378
Total gross deferred tax assets	37,264,439	33,493,680
Less valuation allowance	(37,264,439)	$ (33,493,680)
Net deferred tax assets	$ 0