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Income Taxes - Schedule of Reconciliation of Federal Statutory Income Tax Rate to Effective Income Tax Rate (Detail)
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Income Taxes [Abstract]    
Income tax benefit at the federal statutory rate 21.00% 21.00%
State income taxes, net of federal benefit 0.60% 3.20%
Research and development tax credits 1.40% 1.30%
Other (0.40%) (0.60%)
Mark to market gain/loss   1.70%
Change in valuation allowance (22.60%) (26.60%)