Consolidated Statements of Changes in Stockholders' Equity - USD ($)	Total	Common stock	Preferred Stock	Additional paid-in capital	Accumulated deficit
Balance at the beginning (in shares) at Dec. 31, 2018		40,804,189	2,857,143
Balance at the beginning at Dec. 31, 2018	$ 20,907,748	$ 40,804	$ 2,857	$ 119,082,157	$ (98,218,070)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Issuance of shares pursuant to common stock private placement, net of offering costs (in shares)		1,200,000
Issuance of shares pursuant to common stock private placement, net of offering costs	3,708,602	$ 1,200		3,707,402
Issuance of shares of common stock in underwritten public offering, net of offering costs (in shares)		1,818,182
Issuance of shares of common stock in underwritten public offering, net of offering costs	8,975,960	$ 1,818		8,974,142
Exercise of stock options and warrants (in shares)		323,177
Exercise of stock options and warrants	836,188	$ 323		835,865
Restricted Stock Units vested during the period (in shares)		172,500
Restricted stock units vested during period	0	$ 173		(173)
Restricted Stock Units withheld for taxes (in shares)		(6,969)
Restricted stock units withheld for taxes	(33,959)	$ (7)		(33,952)
Shares purchased through employee stock purchase plan (in shares)		73,143
Shares purchased through employee stock purchase plan	210,777	$ 73		210,704
Stock-based compensation	2,462,796			2,462,796
Net loss	(16,072,547)				(16,072,547)
Balance at the end (in shares) at Dec. 31, 2019		44,384,222	2,857,143
Balance at the end at Dec. 31, 2019	20,995,565	$ 44,384	$ 2,857	135,238,941	(114,290,617)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Conversion of preferred stock to common stock (in shares)		8,000,000	(1,600,000)
Conversion of preferred stock to common stock	0	$ 8,000	$ (1,600)	(6,400)
Issuance of shares related to Aevi Merger (in shares)		3,893,361
Issuance of shares related to Aevi Merger	15,495,578	$ 3,894		15,491,684
Issuance of shares pursuant to registered direct offering, net of offering costs (in shares)		1,306,282
Issuance of shares pursuant to registered direct offering, net of offering costs	5,136,184	$ 1,306		5,134,878
Issuance of shares pursuant to common stock private placement, net of offering costs (in shares)		1,951,219
Issuance of shares pursuant to common stock private placement, net of offering costs	3,887,991	$ 1,951		3,886,040
Issuance of shares of common stock in underwritten public offering, net of offering costs (in shares)		15,180,000
Issuance of shares of common stock in underwritten public offering, net of offering costs	35,427,963	$ 15,180		35,412,783
Exercise of stock options and warrants (in shares)		75,239
Exercise of stock options and warrants	114,092	$ 75		114,017
Restricted Stock Units vested during the period (in shares)		111,667
Restricted stock units vested during period	0	$ 111		(111)
Restricted Stock Units withheld for taxes (in shares)		(35,279)
Restricted stock units withheld for taxes	(93,869)	$ (35)		(93,834)
Shares purchased through employee stock purchase plan (in shares)		137,416
Shares purchased through employee stock purchase plan	312,175	$ 137		312,038
Stock-based compensation	6,785,686			6,785,686
Net loss	(63,499,772)				(63,499,772)
Balance at the end (in shares) at Dec. 31, 2020		75,004,127	1,257,143
Balance at the end at Dec. 31, 2020	$ 24,561,593	$ 75,003	$ 1,257	$ 202,275,722	$ (177,790,389)