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Statements of Convertible Preferred Stock and Stockholders' Equity (Deficit) (USD $)
In Thousands, except Share data
Total
Series A Convertible Preferred Stock [Member]
Series A-1 Convertible Preferred Stock [Member]
Common Stock [Member]
Additional Paid-in Capital [Member]
Accumulated Deficit [Member]
Series A convertible preferred stock, Beginning balance at Dec. 31, 2012   $ 9,726us-gaap_TemporaryEquityCarryingAmountAttributableToParent
/ us-gaap_StatementClassOfStockAxis
= us-gaap_SeriesAPreferredStockMember
       
Beginning balance at Dec. 31, 2012 (5,840)us-gaap_StockholdersEquity       11,317us-gaap_StockholdersEquity
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_AdditionalPaidInCapitalMember
(17,157)us-gaap_StockholdersEquity
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_AccumulatedDeficitDuringDevelopmentStageMember
Series A convertible preferred stock, Beginning balance, shares at Dec. 31, 2012   9,726us-gaap_TemporaryEquitySharesIssued
/ us-gaap_StatementClassOfStockAxis
= us-gaap_SeriesAPreferredStockMember
       
Beginning balance, shares at Dec. 31, 2012       5,289,007us-gaap_SharesIssued
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
   
Issuance of common stock, net of offering costs of $114 15,651us-gaap_StockIssuedDuringPeriodValueNewIssues     1us-gaap_StockIssuedDuringPeriodValueNewIssues
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
15,650us-gaap_StockIssuedDuringPeriodValueNewIssues
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_AdditionalPaidInCapitalMember
 
Issuance of common stock, net of offering costs of $114, shares       3,765,230us-gaap_StockIssuedDuringPeriodSharesNewIssues
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
   
Issuance of common stock in exchange for patent and technology rights 12,250us-gaap_StockIssuedDuringPeriodValueAcquisitions       12,250us-gaap_StockIssuedDuringPeriodValueAcquisitions
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_AdditionalPaidInCapitalMember
 
Issuance of common stock in exchange for patent and technology rights, Shares       1,666,666us-gaap_StockIssuedDuringPeriodSharesAcquisitions
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
   
Stock-based compensation expense 1,979us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue       1,979us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_AdditionalPaidInCapitalMember
 
Cash paid in lieu of fractional shares for 1:30 reverse stock split (12)us-gaap_AdjustmentsToAdditionalPaidInCapitalStockSplit       (12)us-gaap_AdjustmentsToAdditionalPaidInCapitalStockSplit
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_AdditionalPaidInCapitalMember
 
Cash paid in lieu of fractional shares for 1:30 reverse stock split, shares       (2,807)us-gaap_StockIssuedDuringPeriodSharesReverseStockSplits
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
   
Common stock issued upon exercise of stock options 5us-gaap_StockIssuedDuringPeriodValueStockOptionsExercised       5us-gaap_StockIssuedDuringPeriodValueStockOptionsExercised
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_AdditionalPaidInCapitalMember
 
Common stock issued upon exercise of stock options, shares       2,000us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
   
Issuance of common stock under employee stock purchase plan 28us-gaap_StockIssuedDuringPeriodValueEmployeeStockPurchasePlan       28us-gaap_StockIssuedDuringPeriodValueEmployeeStockPurchasePlan
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_AdditionalPaidInCapitalMember
 
Issuance of common stock under employee stock purchase plan, shares       11,265us-gaap_StockIssuedDuringPeriodSharesEmployeeStockPurchasePlans
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
   
Exchange of Series A convertible preferred stock into Series A-1 convertible preferred stock 2,000us-gaap_ReclassificationsOfTemporaryToPermanentEquity (2,000)us-gaap_ReclassificationsOfTemporaryToPermanentEquity
/ us-gaap_StatementClassOfStockAxis
= us-gaap_SeriesAPreferredStockMember
2,000us-gaap_ReclassificationsOfTemporaryToPermanentEquity
/ us-gaap_StatementClassOfStockAxis
= us-gaap_NonredeemableConvertiblePreferredStockMember
     
Exchange of Series A convertible preferred stock into Series A-1 convertible preferred stock, shares   (2,000)rxii_ReclassificationsOfTemporaryToPermanentEquityShares
/ us-gaap_StatementClassOfStockAxis
= us-gaap_SeriesAPreferredStockMember
2,000rxii_ReclassificationsOfTemporaryToPermanentEquityShares
/ us-gaap_StatementClassOfStockAxis
= us-gaap_NonredeemableConvertiblePreferredStockMember
     
Conversions of Series A and Series A-1 convertible preferred stock into common stock 434us-gaap_StockIssuedDuringPeriodValueConversionOfConvertibleSecurities (434)us-gaap_StockIssuedDuringPeriodValueConversionOfConvertibleSecurities
/ us-gaap_StatementClassOfStockAxis
= us-gaap_SeriesAPreferredStockMember
    434us-gaap_StockIssuedDuringPeriodValueConversionOfConvertibleSecurities
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_AdditionalPaidInCapitalMember
 
Conversions of Series A and Series A-1 convertible preferred stock into common stock, shares   (434)us-gaap_StockIssuedDuringPeriodSharesConversionOfConvertibleSecurities
/ us-gaap_StatementClassOfStockAxis
= us-gaap_SeriesAPreferredStockMember
  1,056,684us-gaap_StockIssuedDuringPeriodSharesConversionOfConvertibleSecurities
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
   
Fair value of Series A and Series A-1 convertible preferred stock dividends (8,610)us-gaap_AdjustmentsToAdditionalPaidInCapitalDividendsInExcessOfRetainedEarnings       (8,610)us-gaap_AdjustmentsToAdditionalPaidInCapitalDividendsInExcessOfRetainedEarnings
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_AdditionalPaidInCapitalMember
 
Dividends issued on Series A and Series A-1 convertible preferred stock 7,982us-gaap_DividendsPreferredStockPaidinkind 628us-gaap_DividendsPreferredStockPaidinkind
/ us-gaap_StatementClassOfStockAxis
= us-gaap_SeriesAPreferredStockMember
54us-gaap_DividendsPreferredStockPaidinkind
/ us-gaap_StatementClassOfStockAxis
= us-gaap_NonredeemableConvertiblePreferredStockMember
  7,928us-gaap_DividendsPreferredStockPaidinkind
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_AdditionalPaidInCapitalMember
 
Dividends issued on Series A and Series A-1 convertible preferred stock, shares   628us-gaap_PreferredStockDividendsShares
/ us-gaap_StatementClassOfStockAxis
= us-gaap_SeriesAPreferredStockMember
54us-gaap_PreferredStockDividendsShares
/ us-gaap_StatementClassOfStockAxis
= us-gaap_NonredeemableConvertiblePreferredStockMember
     
Net loss (20,925)us-gaap_NetIncomeLoss         (20,925)us-gaap_NetIncomeLoss
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_AccumulatedDeficitDuringDevelopmentStageMember
Series A convertible preferred stock, Ending balance at Dec. 31, 2013   7,920us-gaap_TemporaryEquityCarryingAmountAttributableToParent
/ us-gaap_StatementClassOfStockAxis
= us-gaap_SeriesAPreferredStockMember
       
Ending balance at Dec. 31, 2013 4,942us-gaap_StockholdersEquity   2,054us-gaap_StockholdersEquity
/ us-gaap_StatementClassOfStockAxis
= us-gaap_NonredeemableConvertiblePreferredStockMember
1us-gaap_StockholdersEquity
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
40,969us-gaap_StockholdersEquity
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_AdditionalPaidInCapitalMember
(38,082)us-gaap_StockholdersEquity
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_AccumulatedDeficitDuringDevelopmentStageMember
Series A convertible preferred stock, Ending balance, shares at Dec. 31, 2013   7,920us-gaap_TemporaryEquitySharesIssued
/ us-gaap_StatementClassOfStockAxis
= us-gaap_SeriesAPreferredStockMember
       
Ending balance, shares at Dec. 31, 2013     2,054us-gaap_SharesIssued
/ us-gaap_StatementClassOfStockAxis
= us-gaap_NonredeemableConvertiblePreferredStockMember
11,788,045us-gaap_SharesIssued
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
   
Issuance of common stock, net of offering costs of $114 1,886us-gaap_StockIssuedDuringPeriodValueNewIssues       1,886us-gaap_StockIssuedDuringPeriodValueNewIssues
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_AdditionalPaidInCapitalMember
 
Issuance of common stock, net of offering costs of $114, shares       700,000us-gaap_StockIssuedDuringPeriodSharesNewIssues
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
   
Stock-based compensation expense 1,846us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue       1,846us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_AdditionalPaidInCapitalMember
 
Common stock issued upon exercise of stock options, shares 0us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised          
Issuance of common stock under employee stock purchase plan 61us-gaap_StockIssuedDuringPeriodValueEmployeeStockPurchasePlan       61us-gaap_StockIssuedDuringPeriodValueEmployeeStockPurchasePlan
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_AdditionalPaidInCapitalMember
 
Issuance of common stock under employee stock purchase plan, shares       32,515us-gaap_StockIssuedDuringPeriodSharesEmployeeStockPurchasePlans
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
   
Exchange of Series A convertible preferred stock into Series A-1 convertible preferred stock 3,000us-gaap_ReclassificationsOfTemporaryToPermanentEquity (3,000)us-gaap_ReclassificationsOfTemporaryToPermanentEquity
/ us-gaap_StatementClassOfStockAxis
= us-gaap_SeriesAPreferredStockMember
3,000us-gaap_ReclassificationsOfTemporaryToPermanentEquity
/ us-gaap_StatementClassOfStockAxis
= us-gaap_NonredeemableConvertiblePreferredStockMember
     
Exchange of Series A convertible preferred stock into Series A-1 convertible preferred stock, shares   (3,000)rxii_ReclassificationsOfTemporaryToPermanentEquityShares
/ us-gaap_StatementClassOfStockAxis
= us-gaap_SeriesAPreferredStockMember
3,000rxii_ReclassificationsOfTemporaryToPermanentEquityShares
/ us-gaap_StatementClassOfStockAxis
= us-gaap_NonredeemableConvertiblePreferredStockMember
     
Conversions of Series A and Series A-1 convertible preferred stock into common stock 166us-gaap_StockIssuedDuringPeriodValueConversionOfConvertibleSecurities (166)us-gaap_StockIssuedDuringPeriodValueConversionOfConvertibleSecurities
/ us-gaap_StatementClassOfStockAxis
= us-gaap_SeriesAPreferredStockMember
(3,716)us-gaap_StockIssuedDuringPeriodValueConversionOfConvertibleSecurities
/ us-gaap_StatementClassOfStockAxis
= us-gaap_NonredeemableConvertiblePreferredStockMember
1us-gaap_StockIssuedDuringPeriodValueConversionOfConvertibleSecurities
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
3,881us-gaap_StockIssuedDuringPeriodValueConversionOfConvertibleSecurities
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_AdditionalPaidInCapitalMember
 
Conversions of Series A and Series A-1 convertible preferred stock into common stock, shares   (166)us-gaap_StockIssuedDuringPeriodSharesConversionOfConvertibleSecurities
/ us-gaap_StatementClassOfStockAxis
= us-gaap_SeriesAPreferredStockMember
(3,716)us-gaap_StockIssuedDuringPeriodSharesConversionOfConvertibleSecurities
/ us-gaap_StatementClassOfStockAxis
= us-gaap_NonredeemableConvertiblePreferredStockMember
9,463,712us-gaap_StockIssuedDuringPeriodSharesConversionOfConvertibleSecurities
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
   
Fair value of Series A and Series A-1 convertible preferred stock dividends (4,130)us-gaap_AdjustmentsToAdditionalPaidInCapitalDividendsInExcessOfRetainedEarnings       (4,130)us-gaap_AdjustmentsToAdditionalPaidInCapitalDividendsInExcessOfRetainedEarnings
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_AdditionalPaidInCapitalMember
 
Dividends issued on Series A and Series A-1 convertible preferred stock 3,774us-gaap_DividendsPreferredStockPaidinkind 356us-gaap_DividendsPreferredStockPaidinkind
/ us-gaap_StatementClassOfStockAxis
= us-gaap_SeriesAPreferredStockMember
240us-gaap_DividendsPreferredStockPaidinkind
/ us-gaap_StatementClassOfStockAxis
= us-gaap_NonredeemableConvertiblePreferredStockMember
  3,534us-gaap_DividendsPreferredStockPaidinkind
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_AdditionalPaidInCapitalMember
 
Dividends issued on Series A and Series A-1 convertible preferred stock, shares   356us-gaap_PreferredStockDividendsShares
/ us-gaap_StatementClassOfStockAxis
= us-gaap_SeriesAPreferredStockMember
240us-gaap_PreferredStockDividendsShares
/ us-gaap_StatementClassOfStockAxis
= us-gaap_NonredeemableConvertiblePreferredStockMember
     
Net loss (8,800)us-gaap_NetIncomeLoss         (8,800)us-gaap_NetIncomeLoss
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_AccumulatedDeficitDuringDevelopmentStageMember
Series A convertible preferred stock, Ending balance at Dec. 31, 2014   5,110us-gaap_TemporaryEquityCarryingAmountAttributableToParent
/ us-gaap_StatementClassOfStockAxis
= us-gaap_SeriesAPreferredStockMember
       
Ending balance at Dec. 31, 2014 $ 2,745us-gaap_StockholdersEquity   $ 1,578us-gaap_StockholdersEquity
/ us-gaap_StatementClassOfStockAxis
= us-gaap_NonredeemableConvertiblePreferredStockMember
$ 2us-gaap_StockholdersEquity
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
$ 48,047us-gaap_StockholdersEquity
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_AdditionalPaidInCapitalMember
$ (46,882)us-gaap_StockholdersEquity
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_AccumulatedDeficitDuringDevelopmentStageMember
Series A convertible preferred stock, Ending balance, shares at Dec. 31, 2014   5,110us-gaap_TemporaryEquitySharesIssued
/ us-gaap_StatementClassOfStockAxis
= us-gaap_SeriesAPreferredStockMember
       
Ending balance, shares at Dec. 31, 2014     1,578us-gaap_SharesIssued
/ us-gaap_StatementClassOfStockAxis
= us-gaap_NonredeemableConvertiblePreferredStockMember
21,984,272us-gaap_SharesIssued
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember