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Stock-Based Compensation - Additional Information (Detail) (USD $)
12 Months Ended
Dec. 31, 2012
Dec. 31, 2011
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]    
Maximum shares of common stock authorized for issuance and available for future grants 90,000,000  
Purchase of common stock 63,847,938   
Shares of common stock available for future grants 26,152,062  
Weighted average fair value of options granted $ 0.07  
Forfeiture rate for options granted to employees 5.00%  
Forfeiture rate for options granted to directors 0.00%  
Weighted-average remaining contractual life of options outstanding 9 years 4 months 24 days  
Weighted-average remaining contractual life of options exercisable 9 years 4 months 21 days  
Aggregate intrinsic value of options outstanding $ 1,900  
Aggregate intrinsic value of exercisable options 950  
Stock-based compensation 114,000 (79,000)
Exercise price of options, Minimum $ 0.65  
Exercise price of options, Maximum $ 7.50  
Rxi [Member]
   
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]    
Stock-based compensation 968,000 2,111,000
Unrecognized compensation cost 3,859,000  
Predecessor [Member]
   
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]    
Purchase of common stock 477,191  
Weighted average fair value of options granted $ 0.47 $ 0.98
Forfeiture rate for options granted to employees 15.00%  
Forfeiture rate for options granted to directors 0.00%  
Stock-based compensation $ 283,000 $ 2,111,000
Forfeiture rate for options granted to senior management 8.00%