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CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS (unaudited) - USD ($)
9 Months Ended
Sep. 30, 2021
Sep. 30, 2020
Cash flows from operating activities:    
Net loss $ (45,027,000) $ (27,939,000)
Adjustments to reconcile net loss to net cash used in operating activities    
Stock-based compensation expense 10,346,000 4,761,000
Depreciation and amortization 4,413,000 4,279,000
Noncash operating lease cost 1,732,000 1,048,000
Amortization of premium on short-term investments 1,554,000 63,000
Other 111,000  
Changes in operating assets and liabilities    
Accounts receivable (4,184,000) (2,603,000)
Inventory and other deferred costs 117,000 (1,662,000)
Prepaid expenses and other assets (3,542,000) (2,065,000)
Accounts payable (3,530,000) (1,628,000)
Accrued and other current liabilities 1,839,000 1,174,000
Contract liabilities (18,067,000) (15,383,000)
Operating lease liabilities (952,000) (637,000)
Other long-term liabilities (364,000) 471,000
Net cash used in operating activities (55,554,000) (40,121,000)
Cash flows from investing activities:    
Purchases of available-for-sale debt securities (227,316,000) (80,104,000)
Proceeds from maturities of available-for-sale debt securities 129,783,000 80,510,000
Proceeds from sales of available-for-sale debt securities 5,059,000  
Purchases of property and equipment (7,506,000) (2,409,000)
Net cash used in investing activities (99,980,000) (2,003,000)
Cash flows from financing activities:    
Proceeds from public offerings, net of underwriting discounts and commissions 162,258,000 117,500,000
Payments of costs related to public offerings (342,000) (93,000)
Proceeds from loans 5,167,000  
Repayments of loans (1,857,000)  
Proceeds from exercise of equity awards 3,127,000 2,920,000
Net cash provided by financing activities 168,353,000 120,327,000
Effect of exchange rates on cash, cash equivalents and restricted cash 18,000 (4,000)
Net change in cash, cash equivalents and restricted cash 12,837,000 78,199,000
Cash and cash equivalents, beginning of period 68,525,000 55,046,000
Cash, cash equivalents and restricted cash, end of period 81,362,000 133,245,000
Reconciliation of cash, cash equivalents and restricted cash to the condensed consolidated balance sheets:    
Cash and cash equivalents 79,572,000 133,245,000
Restricted cash, included in other long-term assets 1,790,000  
Total cash, cash equivalents and restricted cash $ 81,362,000 $ 133,245,000