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Equity-based Compensation and Equity Incentive Plans - Schedule of Equity-based Compensation Expenses (Detail) - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2019
Sep. 30, 2018
Sep. 30, 2019
Sep. 30, 2018
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items]        
Equity-based compensation expense $ 1,069 $ 1,031 $ 3,094 $ 3,445
Research and Development Expense        
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items]        
Equity-based compensation expense 353 386 986 1,115
General and Administrative Expense        
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items]        
Equity-based compensation expense $ 716 $ 645 $ 2,108 $ 2,330