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Stock-based compensation - Employee Stock Purchase Plan (Details)
$ in Thousands
12 Months Ended
Dec. 18, 2018
item
shares
Dec. 31, 2021
USD ($)
shares
Dec. 31, 2020
USD ($)
shares
Dec. 31, 2019
USD ($)
shares
Stock-based compensation        
Shares reserved for issuance | shares   41,457,000 39,129,000  
Assumptions used to estimate fair value of each stock-based award on the grant date        
Stock-based compensation expense   $ 7,711 $ 8,118 $ 8,539
Proceeds from the issuance of common stock, net   $ 6,723 $ 106,059  
Employee Stock purchase plan        
Stock-based compensation        
Percent of common stock at market price to be purchased 85.00%      
Number of vesting periods | item 2      
Vesting period 6 months      
Shares reserved for issuance | shares 2,000,000 1,190,000 1,300,000  
Assumptions used to estimate fair value of each stock-based award on the grant date        
Risk-free interest rate (as a percent)   0.07% 1.04% 2.26%
Volatility (as a percent)   68.00% 109.00% 88.00%
Expected term   6 months 6 months 6 months
Stock-based compensation expense   $ 100 $ 100 $ 400
Issuance of common stock under ESPP | shares   110,060 358,193 341,701
Proceeds from the issuance of common stock, net   $ 200 $ 400 $ 400