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Stock-based compensation - Stock Options (Details) - Stock options - USD ($)
$ / shares in Units, $ in Thousands
9 Months Ended 12 Months Ended
Sep. 30, 2021
Sep. 30, 2020
Dec. 31, 2020
Shares      
Outstanding at the beginning of the period (in shares) 12,690,745    
Granted (in shares) 1,652,863    
Exercised (in shares) (565,891)    
Forfeited/cancelled (in shares) (830,708)    
Outstanding at the end of the period (in shares) 12,947,009   12,690,745
Vested at the end of the period (in shares) 8,454,091    
Weighted-average exercise price per share      
Outstanding at the beginning of the period (in dollars per share) $ 3.90    
Granted (in dollars per share) 2.78    
Exercised (in dollars per share) 1.59    
Forfeited/cancelled (in dollars per share) 3.71    
Outstanding at the end of the period (in dollars per share) 3.87   $ 3.90
Vested at the end of the period (in dollars per share) $ 4.54    
Weighted-average remaining contractual term      
Outstanding at the end of the period 6 years 1 month 6 days   6 years 6 months
Vested at the end of the period 4 years 9 months 18 days    
Aggregate intrinsic value      
Outstanding at the beginning of the period (in dollars) $ 3,390    
Outstanding at the end of the period (in dollars) 10,140   $ 3,390
Vested at the end of the period (in dollars) $ 6,720    
Assumptions used to estimate fair value of each stock-based award on the grant date      
Risk-free interest rate (as a percent) 0.76% 0.75%  
Volatility (as a percent) 95.00% 94.00%  
Dividend yield (as a percent) 0.00% 0.00%  
Expected term 5 years 10 months 24 days 5 years 9 months 18 days